Amoxicillin

Amoxicillin View full size
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$24.95

250mg - 30 capsules
250mg - 90 capsules
500mg - 90 capsules
500mg - 30 capsules

Amoxicillin is an antibiotic of the group penicillin, which is used in treating various infectious diseases induced by bacteria.

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Amoxicillin

Amoxicillin Amoxicillin is an antibiotic of the group penicillin, which is used in treating various infectious diseases. It is available in the form of capsules 250mg and 500mg
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Amoxicillin is an antibiotic of the group penicillin, which is used in treating various infectious diseases induced by bacteria.

Amoxicillin

Qualitative and quantitative composition: Amoxicillin is available in 250 mg and 500 mg dosage of Amoxicillin Trihydrate filled into capsules.

Pharmacological action: Amoxicillin is extended spectrum of Penicillins, aminopenicillin to be precise, which kills bacteria through inhibition of bacterial cell wall synthesis. Bacteria may show resistance to amoxicillin by producing β- lactamases to hydrolyze aminopenicillins or through modification of penicillin-binding proteins. Some bacteria also become impermeable to Amoxicillin thus showing resistance.

Therapeutic indications: To preserve the efficiency of amoxicillin and to cut down the expansion of drug-resistant bacteria (resistant to amoxicillin and other antibiotics) amoxicillin should be given in the treatment of infections proven or strongly suspected to be caused by bacteria. Diseases like bronchitis, pneumonia, gonorrhea, and infections in ENT, UTI and skin can be treated with Amoxicillin. The ulcer producing bacteria Helicobacter pylori infections can also be healed by using Amoxicillin in combination with other medication. Amoxicillin is ineffective against viral infections.

Contraindications: Amoxicillin is contraindicated in patients with penicillin hypersensitivity. Patients having a cross-allergy to other β-lactams such as cephalosporins are also included. Other conditions like acute lymphatic leukemia, viral infections or infectious mononucleosis should be taken into consideration.

Special warnings and precautions for use: Parenteral use of amoxicillin instead of oral administration is advisable for patients suffering from diarrhea and vomiting.

In case of patients with allergies, asthma and renal impairment, amoxicillin should be administered with caution in reduced doses, followed by proper symptomatic medication if needed. Sometimes the use of amoxicillin for prolonged period may result in overgrowth of organisms which are not susceptible to amoxicillin (like yeasts). So such patients should be closely monitored. Patients receiving high dose of should intake sufficient fluid to avoid amoxicillin crystalluria.

Interaction with other medicinal products: Like other broad spectrum antibiotics, amoxicillin may lessen the effectiveness of oral contraceptives. Allergic reaction in the skin is possible if amoxicillin and allopurinol are used together. Other notable considerations for concurrent use are a prolongation of prothrombin time (anticoagulant) increased absorption of digoxin, reduction of antibacterial action with tetracyclines, macrolides, chloramphenicol & sulfonamides; false positive readings of glucose in urine.

Undesirable effects: Has little adverse effect on blood and lymphatic system, immune system (severe allergic reactions may occur in rare cases), nervous system (some reports of dizziness and convulsions).

Gastrointestinal disorders are common (diarrhea and nausea, but no vomiting), discoloration of teeth in children (superficial) has been reported (good oral hygiene will help), skin rashes are also quite common.

Hepatobiliary, renal and urinary tract disorders are extremely rare. Use of amoxicillin for prolonged periods or repeatedly may result in colonization and superinfection of resistant organisms like yeast causing vaginal and oral candidiasis.

Interesting facts:

  • Though the oldest form of antibiotics, Amoxicillin 250mg is most commonly prescribed antibiotic around the world.
  • Penicillins can be produced both chemically (by altering 6-aminopenicillanic acid) and biosynthetically (through fermentation using the mold Penicillium).

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